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Crystal L. Mackall delivers a keynote address at the AACR IO Conference on Discovery and Innovation in Cancer Immunology

Science and Education

tooltip iconAACR Fellow Crystal L. Mackall MD, FAACR, delivers a keynote address on “CAR T cell therapies for solid cancers” at the AACR IO Conference on Discovery and Innovation in Cancer Immunology.

Scientific Leadership

AACR is at the epicenter of the cancer research community, bringing together critical stakeholders and forging the collaborations needed to expand the frontiers of cancer science and medicine and drive progress for cancer patients.

NEW TASK FORCES

AACR shapes the landscape of cancer research through its scientific task forces, convening experts from multiple disciplines to define, evaluate, and foster emerging areas of inquiry. Task forces focus attention and resources on these promising areas, drawing new investigators into the field to accelerate discovery. AACR launched two new task forces in 2025:

  • Aging and Cancer: Stress and Other Risk Factors. This task force was formed to advance our understanding of the extrinsic and intrinsic sources of aging, including stress, and their links to cancer. The mission of the new task force—which is chaired by David A. Tuveson, MD, PhD, FAACR, Electra D. Paskett, PhD, MPH, FAACR, and Sheila A. Stewart, PhD—is to distinguish between correlative features and causative drivers of aging (such as obesity and chronobiology disturbances, social and economic stress, and cellular stress) to improve the prevention, interception, and treatment of cancer.
AACR Aging and Cancer Task Force Chairs David A. Tuveson, Electra D. Paskett, and Sheila A. Stewart
  • Cancer Molecular Imaging and Theranostics. Led by cochairs Kayvan R. Keshari, PhD, David R. Piwnica-Worms, MD, PhD, and Julie L. Sutcliffe, PhD, this new task force fosters research on novel molecular targeting; explores the biological mechanisms that drive clinical response; and provides a forum for research findings on molecular imaging, diagnostics, biomarkers, and radiopharmaceutical therapy.
AACR Cancer Molecular Imaging and Theranostics Task Force Chairs Kayvan R. Keshari, David R. Piwnica-Worms, and Julie L. Sutcliffe

Science Education, Career Development, and Continuing Medical Education

Continued progress against cancer depends on a diverse workforce that is supported at all career levels and trained to make the next wave of paradigm-shifting discoveries. AACR took bold steps in 2025 to sustain and expand the pipeline of cancer scientists and clinicians.

AACR LAUNCHES NEW EDUCATION DIVISION

In March, to ensure the stability and readiness of the cancer research enterprise, AACR reorganized several existing departments and created new ones to establish an Education Division with a stronger focus on the recruitment, education, and training of AACR members. The new division consists of five departments, each of which is optimized to meet a critical need of AACR members:

  • Membership. This department focuses on member recruitment, benefits, and engagement to expand AACR’s member base around the world.
  • Professional Development. This new department is working to expand the career advancement programs that have typically been held at the AACR Annual Meeting, launching new initiatives that will take place throughout the year and around the world.
  • Constituency Groups. For more than 25 years, the AACR Women in Cancer Research (WICR) and Minorities in Cancer Research (MICR) membership groups have been dedicated to meeting the professional needs and supporting the careers of women and minorities working in cancer science and medicine. This new department focuses on enhancing and expanding the critical programs of these distinguished groups.
  • Continuing Medical Education. Formerly the AACR Office of CME, this department works to improve physicians’ knowledge of critical aspects of basic cancer research as well as their ability to apply that knowledge to the clinical practice of oncology.
  • Education and Training. This new department works to expand AACR’s slate of educational workshops, increasing the number of in-person offerings and launching new online programs to enhance AACR’s position as a global leader in scientific education.

AACR STUDENT MEMBERSHIP: FOSTERING THE NEXT GENERATION OF LEADERS FOR 25 YEARS

In 2025, AACR celebrated the 25th anniversary of the establishment of the Student Member category, which provides high school, undergraduate, and postbaccalaureate students with an opportunity to participate in scientific programs and professional development activities.

  • AACR Programs for Undergraduate Students. Since 1997, AACR has offered travel awards to support attendance at the AACR Annual Meeting for meritorious third-year undergraduate students majoring in science, to inspire these emerging scientists to pursue careers in cancer research. In April, AACR brought 22 Undergraduate Scholar Award recipients to the Annual Meeting in Chicago to explore the latest advances in cancer science and medicine.
  • In addition, more than 300 undergraduate students attended the AACR Annual Meeting to participate in the annual AACR Undergraduate Student Caucus and Poster Competition. Many of the students presented their work in a poster session and received feedback on their research from AACR leaders. Presenters of the most highly rated posters received The Margaret Foti Foundation Undergraduate Prizes for Cancer Research, which are funded by AACR Chief Executive Officer Margaret Foti, PhD, MD (hc), to encourage college students to pursue careers in cancer research.
2024-2025 AACR Undergraduate Scholar Awardees
  • In addition, more than 300 undergraduate students attended the AACR Annual Meeting to participate in the annual AACR Undergraduate Student Caucus and Poster Competition. Many of the students presented their work in a poster session and received feedback on their research from AACR leaders. Presenters of the most highly rated posters received The Margaret Foti Foundation Undergraduate Prizes for Cancer Research, which are funded by AACR Chief Executive Officer Margaret Foti, PhD, MD (hc), to encourage college students to pursue careers in cancer research.
  • AACR Special Program for High School Students. Hosted by the Science Education and Career Advancement Committee, the AACR Special Program for High School Students is designed to educate and inspire the next generation of cancer researchers. In 2025, AACR hosted more than 500 high school students for special programs at the AACR Annual Meeting in April and at the AACR Conference on the Science of Cancer Health Disparities in September. The students attended lectures on cancer development and engaged with scientist mentors to explore careers in cancer science and medicine.
Participants in the AACR Special High Program for High School Students held at the AACR Annual Meeting 2025.

Meetings and Educational Workshops

AACR meetings and educational workshops bring the latest advances in cancer science to researchers around the world. AACR worked with seven scientific organizations and institutions to convene 26 meetings and workshops in five countries in 2025, exploring and advancing the frontiers of cutting-edge cancer science.

The 2025 meeting series included a new conference designed to set the research agenda for the cancer immunology community. The AACR IO conference on Discovery and Innovation in Cancer Immunology (held February 23–26 in Los Angeles) showcased the latest basic, translational, and clinical research in immunology, inflammation, and immunotherapies for cancer, including immuno-oncology drugs, inflammatory modulators, vaccines, and cellular therapies. Chaired by former AACR President Antoni Ribas, MD, PhD, FAACR, the inaugural edition of this annual conference featured nine keynote addresses by leaders in the field, including seven Fellows of the AACR Academy—led by Nobel Laureate James P. Allison, PhD, FAACR.

Another new conference in 2025 addressed an issue of critical concern to the cancer research community. The incidence of early-onset cancers (occurring before age 50) has been rapidly increasing over the past 50 years, likely due to changing patterns of exposure in early life. The first-ever AACR Special Conference on the Rise in Early-Onset Cancers (held December 10–13 in Montreal, Quebec, Canada) explored the causes and mechanisms of development of early-onset cancers and discussed how to apply that knowledge to interventions. Organized by Cochairs Andrea Cercek, MD, former AACR President Elizabeth M. Jaffee, MD, FAACR, and Timothy R. Rebbeck, PhD, FAACR, the conference featured keynote addresses by Tomi Akinyemiju, PhD, and Leonardo Trasande, MD.

2025 MEETINGS AND SPECIAL CONFERENCES


TRANSLATING TARGETED THERAPIES IN COMBINATION WITH RADIOTHERAPY

In Association With the AACR Precision Combination Therapy Task Force

January 26–29; San Diego, California
Cochairs: Silvia C. Formenti, MD, FAACR, Albert C. Koong, MD, PhD, and Quynh-Thu Le, MD

DNA METHYLATION, CLONAL HEMATOPOIESIS, AND CANCER

February 1–4; San Diego, California
Cochairs: Stephen B. Baylin, MD, FAACR, Margaret A. Goodell, PhD, FAACR, and Peter A. Jones, PhD, DSc, FAACR

13TH AACR-JCA JOINT CONFERENCE: FROM CANCER DISCOVERY SCIENCE TO THERAPEUTIC INNOVATION

February 1–5; Maui, Hawaii
Organizing Committee Cochairs: Catherine J. Wu, MD, FAACR, and Hiroyuki Mano, MD, PhD

AACR IO
DISCOVERY AND INNOVATION IN CANCER IMMUNOLOGY: REVOLUTIONIZING TREATMENT THROUGH IMMUNOTHERAPY

February 23–26; Los Angeles, California
Chair: Antoni Ribas, MD, PhD, FAACR

FUNCTIONAL AND GENOMIC PRECISION MEDICINE IN CANCER: DIFFERENT PERSPECTIVES, COMMON GOALS

March 11–13; Boston, Massachusetts
Cochairs: Anthony G. Letai, MD, PhD, Elaine R. Mardis, PhD, FAACR, and Peter Horak, MD, PhD, and Alice Soragni, PhD

AACR ONCOLOGY INDUSTRY PARTNERING EVENT

April 24–25; Chicago, Illinois
Cochairs: Michael A. Caligiuri, MD, FAACR, Christiana Bardon, MD, MBA, and William N. Hait, MD, PhD, FAACR

AACR ANNUAL MEETING 2025

April 25–30; Chicago, Illinois
Chairs: Lillian L. Siu, MD, FAACR, and Matthew G. Vander Heiden, MD, PhD

INTERNATIONAL CONFERENCE ON MALIGNANT LYMPHOMA (ICML)

In Cooperation With the AACR

June 17–21; Lugano, Switzerland
Organizing Committee Chairman: Francesco Bertoni, MD

THIRD JCA-AACR PRECISION CANCER MEDICINE INTERNATIONAL CONFERENCE: NEW FRONTIERS IN PRECISION CANCER MEDICINE THROUGH INNOVATIVE MODALITIES

June 28–30; Kyoto, Japan
Chairs: Victor Velculescu, MD, PhD, FAACR, and Motohiro Kato, MD, PhD

ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING

July 10–12; Montreal, Quebec, Canada
Cochairs: Valentina Boeva, PhD, Marzyeh Ghassemi, PhD, Benjamin Haibe-Kains, PhD, and Bo Wang, PhD

THE SCIENCE OF CANCER HEALTH DISPARITIES

In Association With the AACR Minorites in Cancer Research Council (MICR)

September 18–21; Baltimore, Maryland
Cochairs: Ysabel Duron, Christopher R. Flowers, MD, Scarlett L. Gomez, MPH, PhD, Carmen E. Guerra, MD, MSCE, and Lauren E. McCullough, PhD

ADVANCES IN OVARIAN CANCER RESEARCH

September 19–21; Denver, Colorado
Cochairs: Ronald J. Bukanovich, MD, PhD, Jung-Min Lee, MD, Elizabeth M. Swisher, MD, and Oladapo Yeku, MD, PhD

MECHANISMS OF CANCER IMMUNITY AND CANCER-RELATED AUTOIMMUNITY

In Association With the AACR Cancer Immunology Working Group

September 24–27; Montreal, Quebec, Canada
Cochairs: Ana C. Anderson, PhD, Sandra Demaria, MD, Adekunle Odunsi, MD, PhD, and E. John Wherry, PhD, FAACR

DISCOVERY AND INNOVATION IN PEDIATRIC CANCER: FROM BIOLOGY TO BREAKTHROUGH THERAPIES

In Association With the AACR Pediatric Cancer Working Group

September 25–28; Boston, Massachusetts
Cochairs: Alanna J. Church, MD, Meredith S. Irwin, MD, and Charles W.M. Roberts, MD, PhD

ADVANCES IN PANCREATIC CANCER RESEARCH: EMERGING SCIENCE DRIVING TRANSFORMATIVE SOLUTIONS

September 28–October 1; Boston, Massachusetts
Cochairs: Andrew J. Aguirre, MD, PhD, Edna Cukierman, PhD, Susan Tsai, MD, MHS, David A. Tuveson, MD, PhD, FAACR, and Laura DeLong Wood, MD, PhD

AACR-NCI-EORTC INTERNATIONAL CONFERENCE ON MOLECULAR TARGETS AND CANCER THERAPEUTICS

October 22–26; Boston, Massachusetts
Scientific Committee Cochairs: Ryan B. Corcoran, MD, PhD, Tim F. Greten, MD, and Elena Garralda, MD, PhD

AACR-KCA JOINT CONFERENCE ON PRECISION MEDICINE IN CANCER

November 13–15; Busanjin-gu, Korea
Cochairs: Se-Hoon Lee, MD, PhD, and Ricky W. Johnstone, PhD

CANCER EVOLUTION: THE DYNAMICS OF PROGRESSION AND PERSISTENCE

In Association With the AACR Cancer Evolution Working Group

December 4–6; Albuquerque, New Mexico
Cochairs: Mariam Jamal-Hanjani, MD, PhD, Kenneth J. Pienta, MD, and Mara H. Sherman, PhD

SAN ANTONIO BREAST CANCER SYMPOSIUM

December 9–12; San Antonio, Texas
Codirectors: Carlos L. Arteaga, MD, FAACR, and Virginia G. Kaklamani, MD

THE RISE IN EARLY ONSET CANCERS: KNOWLEDGE GAPS AND RESEARCH OPPORTUNITIES

December 10–13; Montreal, Quebec, Canada
Cochairs: Andrea Cercek, MD, Elizabeth M. Jaffee, MD, FAACR, and Timothy R. Rebbeck, PhD, FAACR

2025 EDUCATIONAL WORKSHOPS


EORTC-ESMO-AACR METHODS IN CLINICAL CANCER RESEARCH WORKSHOP

June 14–19; Sint-Michielsgestel, Netherlands
Codirectors: Saskia Litiere, PhD, Christoph Massard, MD, PhD, and Patricia M. LoRusso, DO, PhD (hc), FAACR

ASCO/AACR METHODS IN CLINICAL CANCER RESEARCH

July 20–25; La Jolla, California
Codirectors: Julie M. Vose, MBA, MD, Wendy B. London, PhD, and Timothy A. Yap, MBBS, PhD, FRCP

MOLECULAR BIOLOGY IN CLINICAL ONCOLOGY

July 20–26; Coronado, California
Director: Ross L. Levine, MD
Codirectors: Christine M. Lovly, MD, PhD, and Jean Y. Tang, MD, PhD

INTEGRATIVE MOLECULAR EPIDEMIOLOGY: BRIDGING CANCER BIOLOGY AND PRECISION MEDICINE

July 21–25; Philadelphia, Pennsylvania
Codirectors: Sophia H.L. George, PhD, Peter Kraft, PhD, and Elizabeth A. Platz, MPH, ScD

TRANSLATIONAL CANCER RESEARCH FOR BASIC SCIENTISTS

October 5–10; Cambridge, Massachusetts
Codirectors: Ryan B. Corcoran, MD, PhD, George D. Demetri, MD, FAACR, and Elaine R. Mardis, PhD, FAACR

THE ROBERT A. WINN EXCELLENCE IN CLINICAL TRIALS AWARD PROGRAM: WINN-AACR DESIGN AND IMPLEMENTATION OF CLINICAL TRIALS WORKSHOP

November 17–21; Albuquerque, New Mexico
Codirectors: Roy S. Herbst, MD, PhD, Priscilla E. Pemu, MD, Yu Shyr, PhD, FAACR, and Robert A. Winn, MD, FAACR

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